SAFETY DATA SHEET
ImmEdge Barrier Pen for in Situ Hybridisation
1. IDENTIFICATION
Product Identifiers
Product Name:
ImmEdge Barrier Pen
Other Names:
ImmEdge™ Pen; ImmEdge barrier pen
Product Number(s):
ID320; 22312; H-4000
CAS Number:
Not available
Recommended use of the chemical and restriction on use
Laboratory use
Company Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
Emergency Contact Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Flammable liquids Category 4: Combustible liquid.
Skin corrosion/irritation Category 2: Causes skin irritation.
Serious eye damage/eye irritation Category 2: Causes serious eye irritation.
Carcinogenicity Category 2: Suspected of causing cancer (Inhalation).
Specific target organ toxicity - Single exposure, Category 3: Narcosis May cause drowsiness or dizziness.
Specific target organ toxicity - Single exposure, Category 3: Respiratory tract irritation May cause respiratory irritation.
Specific target organ toxicity (repeated exposure) Category 2: May cause damage to organs (liver) through prolonged or repeated exposure (Inhalation).
Skin corrosion/irritation Category 2: Causes skin irritation.
Serious eye damage/eye irritation Category 2: Causes serious eye irritation.
Carcinogenicity Category 2: Suspected of causing cancer (Inhalation).
Specific target organ toxicity - Single exposure, Category 3: Narcosis May cause drowsiness or dizziness.
Specific target organ toxicity - Single exposure, Category 3: Respiratory tract irritation May cause respiratory irritation.
Specific target organ toxicity (repeated exposure) Category 2: May cause damage to organs (liver) through prolonged or repeated exposure (Inhalation).
Label Elements


Signal Words
Warning
Hazard Statement(s)
Combustible liquid.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
May cause drowsiness or dizziness.
Suspected of causing cancer (Inhalation).
May cause damage to organs (liver) through prolonged or repeated exposure (Inhalation).
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
May cause drowsiness or dizziness.
Suspected of causing cancer (Inhalation).
May cause damage to organs (liver) through prolonged or repeated exposure (Inhalation).
Precautionary Statement(s)
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
Avoid breathing dust/fume/gas/mist/vapours/spray.
Wash hands, forearms and face thoroughly after handling.
Use only outdoors or in a well-ventilated area.
Wear eye protection, protective gloves.
In case of fire: Use ABC-powder, carbon dioxide (CO₂), alcohol resistant foam, foam, sand to
extinguish.
Store in a well-ventilated place. Keep container tightly closed.
Store in a well-ventilated place. Keep cool.
Store locked up.
Dispose of contents/container to hazardous or special waste collection point, in accordance with
local, regional, national and/or international regulation.
Do not handle until all safety precautions have been read and understood.
Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
Avoid breathing dust/fume/gas/mist/vapours/spray.
Wash hands, forearms and face thoroughly after handling.
Use only outdoors or in a well-ventilated area.
Wear eye protection, protective gloves.
In case of fire: Use ABC-powder, carbon dioxide (CO₂), alcohol resistant foam, foam, sand to
extinguish.
Store in a well-ventilated place. Keep container tightly closed.
Store in a well-ventilated place. Keep cool.
Store locked up.
Dispose of contents/container to hazardous or special waste collection point, in accordance with
local, regional, national and/or international regulation.
Primary route(s) of entry
Primary route of entry may be skin, eyes, inhalation or ingestion
Human Health
Inhalation:
If inhaled: Remove person to fresh air and keep comfortable for breathing.
Ingestion:
Call a POISON CENTER or doctor/physician if you feel unwell.
Eyes:
Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
If exposed or concerned: Get medical advice/attention. If eye irritation persists: Get medical advice/attention.
If exposed or concerned: Get medical advice/attention. If eye irritation persists: Get medical advice/attention.
Skin:
If on skin: Wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
Environment
Harmful to aquatic life with long lasting effects
Collect on absorbent material and dispose of according to federal, state and local environmental regulations.
Collect on absorbent material and dispose of according to federal, state and local environmental regulations.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Name
CAS No.
Content (w/w)
Classification
Organic solvent
Not Available
>70%
Trade secret, not disclosed by the manufacturer. See information is section 16
4. FIRST AID MEASURES
Ingestion
Call a poison center/doctor/physician if you feel unwell.
Inhalation
Remove person to fresh air and keep comfortable for breathing. Call a poison center/doctor/physician if you feel unwell.
Skin Contact
Wash thoroughly with water for at least 15 minutes. Obtain medical attention.
Eye Contact
Wash thoroughly with water for at least 15 minutes. Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
Other Information
Symptoms/effects : May cause drowsiness or dizziness.
Symptoms/effects after inhalation : May cause respiratory irritation.
Symptoms/effects after skin contact : Irritation.
Symptoms/effects after eye contact : Eye irritation
Symptoms/effects after inhalation : May cause respiratory irritation.
Symptoms/effects after skin contact : Irritation.
Symptoms/effects after eye contact : Eye irritation
5. FIREFIGHTING MEASURES
Suitable extinguishing equipment
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
HAZCHEM
Combustible liquid.
Hazardous decomposition products in case of fire : Toxic fumes may be released.
Hazardous decomposition products in case of fire : Toxic fumes may be released.
Special protective equipment and precautions for fire fighters
6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
For non-emergency personnel
Emergency procedures: Ventilate spillage area. No open flames, no sparks, and no smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Avoid contact with skin and eyes.
For emergency responders
Protective equipment : Do not attempt to take action without suitable protective equipment. For further information refer
to section 8: "Exposure controls/personal protection".
Emergency procedures: Ventilate spillage area. No open flames, no sparks, and no smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Avoid contact with skin and eyes.
For emergency responders
Protective equipment : Do not attempt to take action without suitable protective equipment. For further information refer
to section 8: "Exposure controls/personal protection".
Environmental precautions
Avoid release to the environment.
Methods and materials for containment and clean up
Collect on absorbent material and dispose of according to federal, state and local environmental regulations.
Dispose of materials or solid residues at an authorised site.
Dispose of materials or solid residues at an authorised site.
7. HANDLING AND STORAGE
Precautions for safe handling
Precautions for safe handling : Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
Wear personal protective equipment. Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Use only outdoors or in a well-ventilated area. Avoid contact with skin and eyes.
Hygiene measures : Wash contaminated clothing before reuse. Do not eat, drink or smoke when using this product.
Always wash hands after handling the product.
Wear personal protective equipment. Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Use only outdoors or in a well-ventilated area. Avoid contact with skin and eyes.
Hygiene measures : Wash contaminated clothing before reuse. Do not eat, drink or smoke when using this product.
Always wash hands after handling the product.
Conditions for safe storage
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Standards
Material
TWA ppm
TWA mg/m3
STEL ppm
STEL mg/m3
Organic solvent (Trade secret)
0.1ppm
-
-
-
Engineering controls
Appropriate engineering controls : Ensure good ventilation of the work station.
Environmental exposure controls : Avoid release to the environment.
Environmental exposure controls : Avoid release to the environment.
Personal protective equipment
Eye and face protection
Chemical safety goggles.
Skin protection
Compatible chemical-resistant gloves. Wear suitable protective clothing.
Body protection
Compatible chemical-resistant gloves.
Respiratory protection
In case of insufficient ventilation, wear suitable respiratory equipment.
9. PHYSICAL AND CHEMICAL PROPERTIES
General information
Appearance
Clear liquid, light blue
Odour
Not applicable
pH
Not applicable
Vapour Pressure
Not applicable
Density
Not applicable
Boiling Point
69 °C
Melting Point
Not applicable
Solubility
Not applicable
Specific Gravity of Density
Not applicable
Flash Point
Non-flammable
Flammable (Explosive) Limits
Not applicable
Ignition Temperature
Not applicable
Formula
Not applicable
10. STABILITY AND REACTIVITY
Reactivity
The product is non-reactive under normal conditions of use, storage and transport
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use
Conditions to avoid
Avoid contact with hot surfaces. Heat. No flames, no sparks. Eliminate all sources of ignition.
Incompatible materials
No additional information available. Under normal conditions of storage and use, hazardous decomposition products should not be produced.
11. TOXICOLOGICAL INFORMATION
Acute effects
No data available.
Eye contact
Causes serious eye irritation.
Skin contact
Causes skin irritation.
Ingestion
No data available.
Inhalation
No data available.
Toxicity and irritation
Skin corrosion/irritation : Causes skin irritation.
Serious eye damage/irritation : Causes serious eye irritation.
Respiratory or skin sensitization : Not classified
Germ cell mutagenicity : Not classified
Carcinogenicity : Suspected of causing cancer (Inhalation).
Aspiration hazard : Not classified
Viscosity, kinematic : No data available
Symptoms/effects : May cause drowsiness or dizziness.
Symptoms/effects after inhalation : May cause respiratory irritation.
Symptoms/effects after skin contact : Irritation.
Symptoms/effects after eye contact : Eye irritation.
Trade secret compound
LD50 oral rat: > 2000 mg/kg body weight Animal: rat, Guideline: OECD Guideline 401 (Acute Oral Toxicity).
LD50 dermal rat: > 2000 mg/kg body weight Animal: rat, Guideline: OECD Guideline 402 (Acute Dermal Toxicity).
LC50 Inhalation - Rat: ≈ 0.035 mg/l air Animal: rat, Guideline: OECD Guideline 403 (Acute Inhalation Toxicity).
IARC group Status: 2B - Possibly carcinogenic to humans
National Toxicity Program (NTP) Status: Reasonably anticipated to be Human Carcinogen
STOT-single exposure: May cause drowsiness or dizziness. May cause respiratory irritation
STOT-repeated exposure: May cause damage to organs (liver) through prolonged or repeated exposure (Inhalation).
Serious eye damage/irritation : Causes serious eye irritation.
Respiratory or skin sensitization : Not classified
Germ cell mutagenicity : Not classified
Carcinogenicity : Suspected of causing cancer (Inhalation).
Aspiration hazard : Not classified
Viscosity, kinematic : No data available
Symptoms/effects : May cause drowsiness or dizziness.
Symptoms/effects after inhalation : May cause respiratory irritation.
Symptoms/effects after skin contact : Irritation.
Symptoms/effects after eye contact : Eye irritation.
Trade secret compound
LD50 oral rat: > 2000 mg/kg body weight Animal: rat, Guideline: OECD Guideline 401 (Acute Oral Toxicity).
LD50 dermal rat: > 2000 mg/kg body weight Animal: rat, Guideline: OECD Guideline 402 (Acute Dermal Toxicity).
LC50 Inhalation - Rat: ≈ 0.035 mg/l air Animal: rat, Guideline: OECD Guideline 403 (Acute Inhalation Toxicity).
IARC group Status: 2B - Possibly carcinogenic to humans
National Toxicity Program (NTP) Status: Reasonably anticipated to be Human Carcinogen
STOT-single exposure: May cause drowsiness or dizziness. May cause respiratory irritation
STOT-repeated exposure: May cause damage to organs (liver) through prolonged or repeated exposure (Inhalation).
12. ECOLOGICAL INFORMATION
Ecotoxicity
The product is not considered harmful to aquatic organisms or to cause long-term adverse effects in the environment.
Persistence and degradability
No data available.
Bioaccumulative potential
Trade secret compound
Partition coefficient n-octanol/water (Log Pow): 2.1 Source: ECHA
Partition coefficient n-octanol/water (Log Pow): 2.1 Source: ECHA
Other adverse effects
No data available.
13. DISPOSAL CONSIDERATIONS
General information
Waste treatment methods : Dispose of contents/container in accordance with licensed collector's sorting instructions
14. TRANSPORT INFORMATION
ADG label required
HAZCHEM
Combustible liquid.
Hazardous decomposition products in case of fire : Toxic fumes may be released.
Hazardous decomposition products in case of fire : Toxic fumes may be released.
UN Number
Not applicable
Proper shipping name
Not applicable
Transport hazard class
Not applicable
Packing group
III (DOT)
Environmental hazard
No data available.
Special precautions for users
DOT Special Provisions (49 CFR 172.102) : 148 - For domestic transportation, this entry directs to § 173.66 for: a. The standards for transporting a single bulk hazardous material for blasting by cargo tank motor vehicles (CTMV);
and b. The standards for CTMVs capable of transporting multiple hazardous materials for blasting in bulk and non-bulk packagings (i.e, a multipurpose bulk truck (MBT)). IB3 - Authorized IBCs: Metal (31A, 31B and 31N); Rigid plastics (31H1 and 31H2); Composite (31HZ1 and 31HA2, 31HB2, 31HN2, 31HD2 and 31HH2). Additional Requirement: Only liquids
with a vapour pressure less than or equal to 110 kPa at 50 C (1.1 bar at 122 F), or 130 kPa at 55 C (1.3 bar at 131 F) are authorised, except for UN2672 (also see Special Provision IP8 in Table 2 for UN2672).
T1 - 1.5 178.274(d)(2) Normal............. 178.275(d)(2)
TP1 - The maximum degree of filling must not exceed the degree of filling determined by the
following: Degree of filling = 97 / 1 + a (tr - tf) Where: tr is the maximum mean bulk temperature
during transport, and tf is the temperature in degrees celsius of the liquid during filling.
DOT Packaging Exceptions (49 CFR 173.xxx) : 150
DOT Packaging Non Bulk (49 CFR 173.xxx) : 203
DOT Packaging Bulk (49 CFR 173.xxx) : 241
DOT Quantity Limitations Passenger aircraft/rail (49
CFR 173.27): 60 L
DOT Quantity Limitations Cargo aircraft only (49CFR 175.75): 220 L
DOT Vessel Stowage Location : A - The material may be stowed ''on deck'' or ''under deck'' on a cargo vessel and on a
passenger vessel.
and b. The standards for CTMVs capable of transporting multiple hazardous materials for blasting in bulk and non-bulk packagings (i.e, a multipurpose bulk truck (MBT)). IB3 - Authorized IBCs: Metal (31A, 31B and 31N); Rigid plastics (31H1 and 31H2); Composite (31HZ1 and 31HA2, 31HB2, 31HN2, 31HD2 and 31HH2). Additional Requirement: Only liquids
with a vapour pressure less than or equal to 110 kPa at 50 C (1.1 bar at 122 F), or 130 kPa at 55 C (1.3 bar at 131 F) are authorised, except for UN2672 (also see Special Provision IP8 in Table 2 for UN2672).
T1 - 1.5 178.274(d)(2) Normal............. 178.275(d)(2)
TP1 - The maximum degree of filling must not exceed the degree of filling determined by the
following: Degree of filling = 97 / 1 + a (tr - tf) Where: tr is the maximum mean bulk temperature
during transport, and tf is the temperature in degrees celsius of the liquid during filling.
DOT Packaging Exceptions (49 CFR 173.xxx) : 150
DOT Packaging Non Bulk (49 CFR 173.xxx) : 203
DOT Packaging Bulk (49 CFR 173.xxx) : 241
DOT Quantity Limitations Passenger aircraft/rail (49
CFR 173.27): 60 L
DOT Quantity Limitations Cargo aircraft only (49CFR 175.75): 220 L
DOT Vessel Stowage Location : A - The material may be stowed ''on deck'' or ''under deck'' on a cargo vessel and on a
passenger vessel.
Additional information
No data available.
15. REGULATORY INFORMATION
Poisons Schedule Number
SARA 302 - No chemicals in this material are subject to the reporting requirements.
SARA 313 - This material does not contain any chemical components with known CAS numbers that exceed the threshold reporting levels established.
SARA 311/312 Hazards - Fire Hazard, Acute Health Hazard, Chronic Health Hazard.
Trade secret compound
Subject to reporting requirements of United States SARA Section 313
15.2. International regulations
Trade secret compound
Listed on IARC (International Agency for Research on Cancer)
Listed as carcinogen on NTP (National Toxicology Program)
15.3. US State regulations
WARNING: This product can expose you to Trade secret compound, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
SARA 313 - This material does not contain any chemical components with known CAS numbers that exceed the threshold reporting levels established.
SARA 311/312 Hazards - Fire Hazard, Acute Health Hazard, Chronic Health Hazard.
Trade secret compound
Subject to reporting requirements of United States SARA Section 313
15.2. International regulations
Trade secret compound
Listed on IARC (International Agency for Research on Cancer)
Listed as carcinogen on NTP (National Toxicology Program)
15.3. US State regulations
WARNING: This product can expose you to Trade secret compound, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Other Information
Risk phrases:
R60 - May impair fertility
R63 - Possible risk of harm to the unborn child
R67 - Vapors may cause drowsiness and dizziness
R36/37/38 - Irritating to eyes, respiratory system and skin
R48/20 - Harmful: danger of serious damage to health by prolonged exposure through inhalation
Safety phrases:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
S53 - Avoid exposure - obtain special instructions before use.
R60 - May impair fertility
R63 - Possible risk of harm to the unborn child
R67 - Vapors may cause drowsiness and dizziness
R36/37/38 - Irritating to eyes, respiratory system and skin
R48/20 - Harmful: danger of serious damage to health by prolonged exposure through inhalation
Safety phrases:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
S53 - Avoid exposure - obtain special instructions before use.
16. OTHER INFORMATION
SDS preparation date
17 November 2025
Comments
*Chemical name, CAS number and/or exact concentration have been withheld as a trade secret.
The specific chemical\ component identities and/or the exact component percentages of this material may be withheld as trade secrets.
This information is made available to health professionals, employees, and designated representatives in accordance with the applicable provisions of 29 CFR 1910.1200 (I)(1). Trace ingredients (if any) are present in < 1% concentration, (< 0.1% for potential carcinogens, mutagen, and reproductive toxicant, respiratory tract and skin sensitisers in addition to oral/ inhalation acute toxicant in category 1 and 2). None of the trace ingredients contribute significant additional hazards at the concentrations that may be present in this product. All pertinent hazard information has been provided in this document, per the requirements of the Federal Occupational Safety and Health Administration Standard (29 CFR 1910.1200), U.S. State equivalents.
The specific chemical\ component identities and/or the exact component percentages of this material may be withheld as trade secrets.
This information is made available to health professionals, employees, and designated representatives in accordance with the applicable provisions of 29 CFR 1910.1200 (I)(1). Trace ingredients (if any) are present in < 1% concentration, (< 0.1% for potential carcinogens, mutagen, and reproductive toxicant, respiratory tract and skin sensitisers in addition to oral/ inhalation acute toxicant in category 1 and 2). None of the trace ingredients contribute significant additional hazards at the concentrations that may be present in this product. All pertinent hazard information has been provided in this document, per the requirements of the Federal Occupational Safety and Health Administration Standard (29 CFR 1910.1200), U.S. State equivalents.
References
Vector Laboratories Safety Data Sheet ImmEdge™ Pen 27/09/2022 https://prod-vector-labs-wordpress-media.s3.amazonaws.com/productattachments/sds/VL_H-4000_GHSsds.pdf
This Safety Data Sheet (SDS) has been prepared in compliance with the Preparation of Safety Data Sheets for Hazardous Chemicals Code of Practice February 2016. It is the user's responsibility to determine the suitability of this information for adoption of necessary safety precautions. The information published in this SDS has been compiled from the publications listed in Section 16: to the best of our ability and knowledge these publications are considered accurate. We reserve the right to revise Safety Data Sheets as new information becomes available. Copies may be made for non-profit use.